This cover of Esquire is known as one of the best magazine covers of all time, and I believe that is because it is interesting to look at without knowing the background or reference it is making, but when you do know the reference it is extremely interesting. The cover is referencing the stort of Saint Sebastien. The painting below by Andrea Mantegna is one of the most famous images of the saint.
Sebastien is the patron saint of athletes, among other things, who was shot with arrows for his beliefs. The cover is comparing Ali to this saint who never gave up on his beliefs, although he was seriously persecuted for it. When you know the story behind the image it is extremely powerful. A similar example for today's society is the following cover of Rolling Stone:
This is an obvious comparison of Kanye West to the most recognized image in the world, Jesus with the crown of thorns. Both of these covers show these contemporary icons with a reference to past icons. It is more than just looking like the person, it has to do with the beliefs that the person has, not necessarily religious, but the amount of passion these people have for what they do is enough that people may compare it to a religious figure. I believe the Esquire cover is less recognizable and not as easy to connect the story to the image, because I would not have instantly known that it was referencing Saint Sebastien, however in the case of the Kanye cover it is an instant read that it is referencing Jesus, also the text that says the passion of Kanye West makes it clear that they are not calling Kanye a religious figure, just that he is extremely passionate. Although the text does help the understanding, it makes the image not as powerful. The starkness of the Esquire cover makes it stand out. They are both extremely interesting and make strong statements about current icons and their beliefs.